1. Chemical analysis and instrumental analysis
Acetonitrile has been used as an organic modifier and solvent in thin layer chromatography, paper chromatography, spectroscopy, and polarographic analysis in recent years. Due to the fact that high-purity acetonitrile does not absorb ultraviolet light between 200nm and 400nm, a developing application is as a solvent for high-performance liquid chromatography HPLC, which can achieve analytical sensitivity up to 10-9 levels.
2. Solvent for hydrocarbon extraction and separation
Acetonitrile is a widely used solvent, mainly used as the solvent of extractive distillation to separate butadiene from C4 hydrocarbons. Acetonitrile is also used for the separation of other hydrocarbons, such as propylene, isoprene, and methylacetylene, from hydrocarbon fractions. Acetonitrile is also used for some special separations, such as extracting and separating fatty acids from vegetable oil and fish liver oil, to make the treated oil light, pure, and improve its odor, while maintaining the same vitamin content. Acetonitrile is also widely used as a solvent in the pharmaceutical, pesticide, textile, and plastic sectors. [2]
3. Intermediates of synthetic medicine and pesticides
Acetonitrile can be used as an intermediate in the synthesis of various pharmaceuticals and pesticides. In medicine, it is used to synthesize a series of important pharmaceutical intermediates, such as vitamin B1, metronidazole, ethambutol, aminopteridine, adenine and dipyridamole; In pesticides, it is used to synthesize pesticide intermediates such as pyrethroid insecticides and acetoxim. [1]
4. Semiconductor cleaning agent
Acetonitrile is an organic solvent with strong polarity, which has good solubility in grease, inorganic salt, organic matter and macromolecular compound, and can clean grease, wax, fingerprint, corrosive agent and flux residue on silicon wafer. Therefore, high-purity acetonitrile can be used as a semiconductor cleaning agent.
5. Other applications
In addition to the above applications, acetonitrile can also be used as a component of organic synthesis raw materials, catalysts, or transition metal complex catalysts. In addition, acetonitrile is also used in fabric dyeing and coating composites, and it is also an effective stabilizer for chlorinated solvents.
Post time: May-09-2023